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Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics
Mitochondrial oxidative stress is associated with many neurodegenerative diseases, such as traumatic brain injury (TBI). Targeted delivery of antioxidants to mitochondria has failed to translate into clinical success due to their nonspecific cellular localization, poor transport properties across mu...
Autores principales: | Sharma, Anjali, Liaw, Kevin, Sharma, Rishi, Zhang, Zhi, Kannan, Sujatha, Kannan, Rangaramanujam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276292/ https://www.ncbi.nlm.nih.gov/pubmed/30555562 http://dx.doi.org/10.7150/thno.29039 |
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