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In vivo [(64)Cu]CuCl(2) PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis

Given the strong clinical evidence that copper levels are significantly elevated in a wide spectrum of tumors, copper homeostasis is considered as an emerging target for anticancer drug design. Monitoring copper levels in vivo is therefore of paramount importance when assessing the efficacy of coppe...

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Detalles Bibliográficos
Autores principales: Parmar, Arvind, Pascali, Giancarlo, Voli, Florida, Lerra, Luigi, Yee, Eugene, Ahmed-Cox, Aria, Kimpton, Kathleen, Cirillo, Giuseppe, Arthur, Andrew, Zahra, David, Rahardjo, Gita, Liu, Guo Jun, Lengkeek, Nigel, Saletta, Federica, Charil, Arnaud, Kavallaris, Maria, Vittorio, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276294/
https://www.ncbi.nlm.nih.gov/pubmed/30555570
http://dx.doi.org/10.7150/thno.29840