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In vivo [(64)Cu]CuCl(2) PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis
Given the strong clinical evidence that copper levels are significantly elevated in a wide spectrum of tumors, copper homeostasis is considered as an emerging target for anticancer drug design. Monitoring copper levels in vivo is therefore of paramount importance when assessing the efficacy of coppe...
Autores principales: | Parmar, Arvind, Pascali, Giancarlo, Voli, Florida, Lerra, Luigi, Yee, Eugene, Ahmed-Cox, Aria, Kimpton, Kathleen, Cirillo, Giuseppe, Arthur, Andrew, Zahra, David, Rahardjo, Gita, Liu, Guo Jun, Lengkeek, Nigel, Saletta, Federica, Charil, Arnaud, Kavallaris, Maria, Vittorio, Orazio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276294/ https://www.ncbi.nlm.nih.gov/pubmed/30555570 http://dx.doi.org/10.7150/thno.29840 |
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