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Data-Driven-Based Approach to Identifying Differentially Methylated Regions Using Modified 1D Ising Model

BACKGROUND: DNA methylation is essential for regulating gene expression, and the changes of DNA methylation status are commonly discovered in disease. Therefore, identification of differentially methylation patterns, especially differentially methylated regions (DMRs), in two different groups is imp...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Wang, Shudong, Wang, Xinzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276520/
https://www.ncbi.nlm.nih.gov/pubmed/30581840
http://dx.doi.org/10.1155/2018/1070645