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Thrombotic Microangiopathy with Severe Proteinuria Induced by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Carcinoma

Standard therapy for radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC) is multi-targeted kinase inhibitors (m-TKIs), represented by sorafenib and lenvatinib. One of the main target molecules of m-TKIs is vascular endothelial growth factor receptor (VEGF-R). m-TKIs are known to...

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Detalles Bibliográficos
Autores principales: Hyogo, Yasuko, Kiyota, Naomi, Otsuki, Naoki, Goto, Shunsuke, Imamura, Yoshinori, Chayahara, Naoko, Toyoda, Masanori, Nibu, Ken-ichi, Hyodo, Toshiki, Hara, Shigeo, Masuoka, Hiroo, Kasahara, Toshihiko, Ito, Yasuhiro, Miya, Akihiro, Hirokawa, Mitsuyoshi, Miyauchi, Akira, Minami, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276762/
https://www.ncbi.nlm.nih.gov/pubmed/30519176
http://dx.doi.org/10.1159/000494080