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Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

CDH1 and PIK3CA are the two most frequently mutated genes in invasive lobular carcinoma (ILC) of the breast. Transcription profiling has identified molecular subtypes for ILC, one of which, immune-related (IR), is associated with gene expression linked to lymphocyte and macrophage infiltration. Here...

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Detalles Bibliográficos
Autores principales: An, Yeji, Adams, Jessica R., Hollern, Daniel P., Zhao, Anthony, Chang, Stephen G., Gams, Miki S., Chung, Philip E.D., He, Xiaping, Jangra, Rhea, Shah, Juhi S., Yang, Joanna, Beck, Lauren A., Raghuram, Nandini, Kozma, Katelyn J., Loch, Amanda J., Wang, Wei, Fan, Cheng, Done, Susan J., Zacksenhaus, Eldad, Guidos, Cynthia J., Perou, Charles M., Egan, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276789/
https://www.ncbi.nlm.nih.gov/pubmed/30332649
http://dx.doi.org/10.1016/j.celrep.2018.09.056