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Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions

Specific metabolic alterations have recently been observed in cisplatin-resistant cancers. As a result, cisplatin resistance can be overcome by co-administration of pyridoxine, and cisplatin-resistant cancer cells become exquisitely sensitive to killing by inhibitors of poly(ADP-ribose) polymerase,...

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Detalles Bibliográficos
Autores principales: Castedo, Maria, Obrist, Florine, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276841/
https://www.ncbi.nlm.nih.gov/pubmed/30525097
http://dx.doi.org/10.1080/23723556.2018.1526004