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Oncogenic regulatory circuits driven by 19q13 rs11672691 underlies prostate cancer aggressiveness

The 19q13 allele rs11672691 has been reproducibly found in association with aggressive form of prostate cancer, yet the underlying mechanism remains totally unknown. We have recently uncovered a mechanism by which rs11672691 influenced a novel oncogenic regulatory circuit, including HOXA2, PCAT19 an...

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Detalles Bibliográficos
Autores principales: Xia, Ji-Han, Wei, Gong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276850/
https://www.ncbi.nlm.nih.gov/pubmed/30525094
http://dx.doi.org/10.1080/23723556.2018.1516451