Aberrant splicing in B-cell acute lymphoblastic leukemia

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Aberrant splicing is a hallmark of leukemias with mutations in splicing factor (SF)-encoding genes. Here we investigated its prevalence in pediatric B-cell acute lymphoblastic leukemias (B-ALL), where SFs are not mutated. By comparing these samples to normal pro-B cells, we found thousands of aberra...

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Detalles Bibliográficos
Autores principales: Black, Kathryn L, Naqvi, Ammar S, Asnani, Mukta, Hayer, Katharina E, Yang, Scarlett Y, Gillespie, Elisabeth, Bagashev, Asen, Pillai, Vinodh, Tasian, Sarah K, Gazzara, Matthew R, Carroll, Martin, Taylor, Deanne, Lynch, Kristen W, Barash, Yoseph, Thomas-Tikhonenko, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277088/
https://www.ncbi.nlm.nih.gov/pubmed/30357359
http://dx.doi.org/10.1093/nar/gky946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277088/
https://www.ncbi.nlm.nih.gov/pubmed/30357359
http://dx.doi.org/10.1093/nar/gky946

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