Leucine rich repeat kinase 2 (LRRK2) GLY2019SER mutation is absent in a second cohort of Nigerian Africans with Parkinson disease

To date the LRRK2 p.G2019S mutation remains the most common genetic cause of Parkinson disease (PD) worldwide. It accounts for up to 6% of familial and approximately 1.5% of sporadic cases. LRRK2 has a kinase enzymatic domain which provides an attractive potential target for drug therapies and LRRK2...

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Detalles Bibliográficos
Autores principales: Okubadejo, Njideka U., Rizig, Mie, Ojo, Oluwadamilola O., Jonvik, Hallgeir, Oshinaike, Olajumoke, Brown, Emmeline, Houlden, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277104/
https://www.ncbi.nlm.nih.gov/pubmed/30507963
http://dx.doi.org/10.1371/journal.pone.0207984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277104/
https://www.ncbi.nlm.nih.gov/pubmed/30507963
http://dx.doi.org/10.1371/journal.pone.0207984

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