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Thermodynamic characterization for the denatured state of bovine prion protein and the BSE Associated variant E211K
Propagation of transmissible spongiform encephalopathies involves the conversion of cellular prion protein, PrP(C), into a misfolded oligomeric form, PrP(Sc). The most common hereditary prion disease is a genetic form of Creutzfeldt-Jakob disease in humans, in which a mutation in the prion gene resu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277186/ https://www.ncbi.nlm.nih.gov/pubmed/30354921 http://dx.doi.org/10.1080/19336896.2018.1534485 |