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Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis

The expression of the transcription factor SOX4 is increased in many human cancers, however, the pro-oncogenic capacity of SOX4 can vary greatly depending on the type of tumor. Both the contextual nature and the mechanisms underlying the pro-oncogenic SOX4 response remain unexplored. Here, we demons...

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Detalles Bibliográficos
Autores principales: Vervoort, Stephin J, de Jong, Olivier G, Roukens, M Guy, Frederiks, Cynthia L, Vermeulen, Jeroen F, Lourenço, Ana Rita, Bella, Laura, Vidakovic, Ana Tufegdzic, Sandoval, José L, Moelans, Cathy, van Amersfoort, Miranda, Dallman, Margaret J, Bruna, Alejandra, Caldas, Carlos, Nieuwenhuis, Edward, van der Wall, Elsken, Derksen, Patrick, van Diest, Paul, Verhaar, Marianne C, Lam, Eric W-F, Mokry, Michal, Coffer, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277201/
https://www.ncbi.nlm.nih.gov/pubmed/30507376
http://dx.doi.org/10.7554/eLife.27706