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PKCζ Phosphorylates SIRT6 to Mediate Fatty Acid β-Oxidation in Colon Cancer Cells

Protein kinase C (PKC) has critical roles in regulating lipid anabolism and catabolism. PKCζ, a member of atypical PKC family, has been reported to mediate glucose metabolism. However, whether and how PKCζ regulates tumor cells fatty acid β-oxidation are unknown. Here, we report that the phosphoryla...

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Detalles Bibliográficos
Autores principales: Gao, Tian, Li, Meiting, Mu, Guanqun, Hou, Tianyun, Zhu, Wei-Guo, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277223/
https://www.ncbi.nlm.nih.gov/pubmed/30504065
http://dx.doi.org/10.1016/j.neo.2018.11.008