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Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility

Extracellular signal-regulated kinase (ERK) plays critical roles in T cell development in the thymus. Nevertheless, the dynamics of ERK activity and the role of ERK in regulating thymocyte motility remain largely unknown due to technical limitations. To visualize ERK activity in thymocytes, we here...

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Detalles Bibliográficos
Autores principales: Konishi, Yoshinobu, Terai, Kenta, Furuta, Yasuhide, Kiyonari, Hiroshi, Abe, Takaya, Ueda, Yoshihiro, Kinashi, Tatsuo, Hamazaki, Yoko, Takaori-Kondo, Akifumi, Matsuda, Michiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277225/
https://www.ncbi.nlm.nih.gov/pubmed/30508722
http://dx.doi.org/10.1016/j.isci.2018.11.025