Cargando…

Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility

Extracellular signal-regulated kinase (ERK) plays critical roles in T cell development in the thymus. Nevertheless, the dynamics of ERK activity and the role of ERK in regulating thymocyte motility remain largely unknown due to technical limitations. To visualize ERK activity in thymocytes, we here...

Descripción completa

Detalles Bibliográficos
Autores principales:	Konishi, Yoshinobu, Terai, Kenta, Furuta, Yasuhide, Kiyonari, Hiroshi, Abe, Takaya, Ueda, Yoshihiro, Kinashi, Tatsuo, Hamazaki, Yoko, Takaori-Kondo, Akifumi, Matsuda, Michiyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277225/ https://www.ncbi.nlm.nih.gov/pubmed/30508722 http://dx.doi.org/10.1016/j.isci.2018.11.025

Ejemplares similares

A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging
por: Komatsu, Naoki, et al.
Publicado: (2018)

Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis
por: Murai, Shin, et al.
Publicado: (2022)

FRET-Based Detection and Quantification of HIV-1 Virion Maturation
por: Sarca, Anamaria D., et al.
Publicado: (2021)

Experimental pathology by intravital microscopy and genetically encoded fluorescent biosensors
por: Matsuda, Michiyuki, et al.
Publicado: (2020)

Dynamic organelle localization and cytoskeletal reorganization during preimplantation mouse embryo development revealed by live imaging of genetically encoded fluorescent fusion proteins
por: Kiyonari, Hiroshi, et al.
Publicado: (2019)

Animal transgenesis on the fast track in the era of evolving genome editing technologies: report for TT2017 the 14th Transgenic Technology Meeting in Snowbird, Utah
por: Furuta, Yasuhide, et al.
Publicado: (2018)

Functional visualization of NK cell-mediated killing of metastatic single tumor cells
por: Ichise, Hiroshi, et al.
Publicado: (2022)

Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization
por: Fukuhara, Takataro, et al.
Publicado: (2023)

Rho GTPase isoforms in cell motility: Don't fret, we have FRET
por: Donnelly, Sara K, et al.
Publicado: (2014)

Development of an optimized backbone of FRET biosensors for kinases and GTPases
por: Komatsu, Naoki, et al.
Publicado: (2011)

In vivo imaging of inflammatory response in cancer research
por: Konishi, Yoshinobu, et al.
Publicado: (2023)

Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer
por: Komatsubara, Akira T., et al.
Publicado: (2015)

MST1/2 Balance Immune Activation and Tolerance by Orchestrating Adhesion, Transcription, and Organelle Dynamics in Lymphocytes
por: Ueda, Yoshihiro, et al.
Publicado: (2020)

LFA1 Activation: Insights from a Single-Molecule Approach
por: Kondo, Naoyuki, et al.
Publicado: (2022)

Two New FRET Imaging Measures: Linearly Proportional to and Highly Contrasting the Fraction of Active Molecules
por: Yamao, Masataka, et al.
Publicado: (2016)

Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders
por: Sugino, Noriko, et al.
Publicado: (2017)

Activity of Rho-family GTPases during cell division as visualized with FRET-based probes
por: Yoshizaki, Hisayoshi, et al.
Publicado: (2003)

Balancing Thymocyte Adhesion and Motility: A Functional Linkage Between β1 Lntegrins and The Motility Receptor RHAMM
por: Gares, Sheryl L., et al.
Publicado: (2000)

HIV-1 Vif: a guardian of the virus that opens up a new era in the research field of restriction factors
por: Takaori-Kondo, Akifumi, et al.
Publicado: (2013)

Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire(−/−) mice
por: Jin, Rong, et al.
Publicado: (2016)

In vivo imaging reveals PKA regulation of ERK activity during neutrophil recruitment to inflamed intestines
por: Mizuno, Rei, et al.
Publicado: (2014)

Familial Mediterranean Fever Mutations in a Patient with Periodic Episodes of Systemic Pain Deriving from Cancer Bone Metastases
por: Yamashita, Kouhei, et al.
Publicado: (2018)

Analysis of thymocyte MHC specificity with thymocyte hybridomas
Publicado: (1984)

Antigen-Specific Suppression and Immunological Synapse Formation by Regulatory T Cells Require the Mst1 Kinase
por: Tomiyama, Takashi, et al.
Publicado: (2013)

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
por: Shimonaka, Mika, et al.
Publicado: (2003)

Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration
por: Lin, Shuhao, et al.
Publicado: (2021)

TSLP is involved in expansion of early thymocyte progenitors
por: Jiang, Qi, et al.
Publicado: (2007)

Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain
por: Nishino, Tasuku, et al.
Publicado: (2019)

Granulocytic sarcoma of the pancreas on (18)F-FDG PET/CT: A case report
por: Ishii, Akira, et al.
Publicado: (2016)

Comparison of up-front treatments for newly diagnosed immune thrombocytopenia -a systematic review and network meta-analysis
por: Arai, Yasuyuki, et al.
Publicado: (2018)

Efficacy of Dexamethasone for Acute Primary Immune Thrombocytopenia Compared to Prednisolone: A Systematic Review and Meta-analysis
por: Arai, Yasuyuki, et al.
Publicado: (2017)

Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B
por: Mukai, Satomi, et al.
Publicado: (2015)

The critical role of Rap1-GAPs Rasa3 and Sipa1 in T cells for pulmonary transit and egress from the lymph nodes
por: Horitani, Shunsuke, et al.
Publicado: (2023)

Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow
por: Kamioka, Yuji, et al.
Publicado: (2023)

Application of FRET probes in the analysis of neuronal plasticity
por: Ueda, Yoshibumi, et al.
Publicado: (2013)

FRET Measurement of Polymer Response under Shear
por: Iwao, Ryo, et al.
Publicado: (2021)

Pituitary abscess in an HIV-1-infected patient
por: Yamazaki, Hiroyuki, et al.
Publicado: (2017)

Detection of Homing, Proliferation, and Infiltration Sites of Adult T Cell Leukemia Cells in Severe Combined Immunodeficiency Mice Using Radiometric Techniques
por: Takaori‐Kondo, Akifumi, et al.
Publicado: (1995)

Defects in Thymocyte Differentiation and Thymocyte- Stromal Interactions in the Trisomy 16 Mouse
por: Ewart, Janet L., et al.
Publicado: (1992)

CDK1 dependent phosphorylation of hTERT contributes to cancer progression
por: Yasukawa, Mami, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cubppgpgp4u8942999a4tgh339