Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders()()

OBJECTIVES: Remodeling of the extracellular matrix (ECM) is a key event in different lung disorders, such as fibrosis and cancer. The most common cell type in the connective tissue is fibroblasts, which transdifferentiate into myofibroblasts upon activation. All myofibroblasts express α-SMA, which h...

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Detalles Bibliográficos
Autores principales: Holm Nielsen, Signe, Willumsen, Nicholas, Leeming, Diana Julie, Daniels, Samuel Joseph, Brix, Susanne, Karsdal, Morten Asser, Genovese, Federica, Nielsen, Mette Juul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277250/
https://www.ncbi.nlm.nih.gov/pubmed/30504086
http://dx.doi.org/10.1016/j.tranon.2018.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277250/
https://www.ncbi.nlm.nih.gov/pubmed/30504086
http://dx.doi.org/10.1016/j.tranon.2018.11.004

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