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Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice

Inflammation is implicated in epileptogenesis. Activated microglia and macrophages (MG/MΦ) are found in the brains of patients with epilepsy-related diseases and animal models of epilepsy. It is not yet known how the MG/MΦ activation phenotype affects pathological changes in the brain after a single...

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Detalles Bibliográficos
Autores principales: Liu, Jin-Tao, Wu, Sheng-Xi, Zhang, Hua, Kuang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277303/
https://www.ncbi.nlm.nih.gov/pubmed/30112701
http://dx.doi.org/10.1007/s13311-018-0653-0