Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis

Severe Malarial Anemia (SMA), a life-threatening childhood Plasmodium falciparum malaria syndrome requiring urgent blood transfusion, exhibits inflammatory and hemolytic pathology. Differentiating between hypo-haptoglobinemia due to hemolysis or that of genetic origin is key to understand SMA pathog...

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Detalles Bibliográficos
Autores principales: Abah, Samuel Eneọjọ, Burté, Florence, Marquet, Sandrine, Brown, Biobele J., Akinkunmi, Francis, Oyinloye, Gbeminiyi, Afolabi, Nathaniel K., Omokhodion, Samuel, Lagunju, Ikeoluwa, Shokunbi, Wuraola A., Wahlgren, Mats, Dessein, Hélia, Argiro, Laurent, Dessein, Alain J., Noyvert, Boris, Hunt, Lilian, Elgar, Greg, Sodeinde, Olugbemiro, Holder, Anthony A., Fernandez-Reyes, Delmiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277387/
https://www.ncbi.nlm.nih.gov/pubmed/30510258
http://dx.doi.org/10.1038/s41598-018-35944-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277387/
https://www.ncbi.nlm.nih.gov/pubmed/30510258
http://dx.doi.org/10.1038/s41598-018-35944-w

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