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Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis

DNA methylation is a regulatory mechanism in epigenetics that is frequently altered during human carcinogenesis. To detect critical methylation events associated with gastric cancer (GC), we compared three DNA methylomes from gastric mucosa (GM), intestinal metaplasia (IM), and gastric tumor (GT) ce...

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Detalles Bibliográficos
Autores principales: Kim, Hee-Jin, Kang, Tae-Wook, Haam, Keeok, Kim, Mirang, Kim, Seon-Kyu, Kim, Seon-Young, Lee, Sang-Il, Song, Kyu-Sang, Jeong, Hyun-Yong, Kim, Yong Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277407/
https://www.ncbi.nlm.nih.gov/pubmed/30510283
http://dx.doi.org/10.1038/s12276-018-0179-x