MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells

The role of mitochondria dynamics and its molecular regulators remains largely unknown during naïve-to-primed pluripotent cell interconversion. Here we report that mitochondrial MTCH2 is a regulator of mitochondrial fusion, essential for the naïve-to-primed interconversion of murine embryonic stem c...

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Detalles Bibliográficos
Autores principales: Bahat, Amir, Goldman, Andres, Zaltsman, Yehudit, Khan, Dilshad H., Halperin, Coral, Amzallag, Emmanuel, Krupalnik, Vladislav, Mullokandov, Michael, Silberman, Alon, Erez, Ayelet, Schimmer, Aaron D., Hanna, Jacob H., Gross, Atan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277412/
https://www.ncbi.nlm.nih.gov/pubmed/30510213
http://dx.doi.org/10.1038/s41467-018-07519-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277412/
https://www.ncbi.nlm.nih.gov/pubmed/30510213
http://dx.doi.org/10.1038/s41467-018-07519-w

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