Exocyst dynamics during vesicle tethering and fusion

The exocyst is a conserved octameric complex that tethers exocytic vesicles to the plasma membrane prior to fusion. Exocyst assembly and delivery mechanisms remain unclear, especially in mammalian cells. Here we tagged multiple endogenous exocyst subunits with sfGFP or Halo using Cas9 gene-editing,...

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Detalles Bibliográficos
Autores principales: Ahmed, Syed Mukhtar, Nishida-Fukuda, Hisayo, Li, Yuchong, McDonald, W. Hayes, Gradinaru, Claudiu C., Macara, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277416/
https://www.ncbi.nlm.nih.gov/pubmed/30510181
http://dx.doi.org/10.1038/s41467-018-07467-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277416/
https://www.ncbi.nlm.nih.gov/pubmed/30510181
http://dx.doi.org/10.1038/s41467-018-07467-5

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