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Midostaurin reduces Regulatory T cells markers in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy in which the only curative approach is allogeneic stem cell transplant (Allo-HSCT). The recognition and elimination of leukemic clones by donor T-cells contribute significantly to Allo-HSCT success. FLT3-ITD, a common mutation...

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Detalles Bibliográficos
Autores principales: Gutierrez, Lucas, Jang, Miran, Zhang, Tian, Akhtari, Mojtaba, Alachkar, Houda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277419/
https://www.ncbi.nlm.nih.gov/pubmed/30510164
http://dx.doi.org/10.1038/s41598-018-35978-0