Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer

Here we describe the establishment and characterization of an AR+, PSMA+, ERG+, PTEN(−/−), CHD1(+/−) patient-derived xenograft (PDX) model termed ‘C5’, which has been developed from a 60 years old patient suffering from castration-resistant prostate cancer (CRPC). The patient underwent radical prost...

Descripción completa

Detalles Bibliográficos
Autores principales: Lange, Tobias, Oh-Hohenhorst, Su Jung, Joosse, Simon A., Pantel, Klaus, Hahn, Oliver, Gosau, Tobias, Dyshlovoy, Sergey A., Wellbrock, Jasmin, Feldhaus, Susanne, Maar, Hanna, Gehrcke, Renate, Kluth, Martina, Simon, Ronald, Schlomm, Thorsten, Huland, Hartwig, Schumacher, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277427/
https://www.ncbi.nlm.nih.gov/pubmed/30510249
http://dx.doi.org/10.1038/s41598-018-35695-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277427/
https://www.ncbi.nlm.nih.gov/pubmed/30510249
http://dx.doi.org/10.1038/s41598-018-35695-8

Ejemplares similares