Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry

Data independent acquisition (DIA) mass spectrometry is a powerful technique that is improving the reproducibility and throughput of proteomics studies. Here, we introduce an experimental workflow that uses this technique to construct chromatogram libraries that capture fragment ion chromatographic...

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Detalles Bibliográficos
Autores principales: Searle, Brian C., Pino, Lindsay K., Egertson, Jarrett D., Ting, Ying S., Lawrence, Robert T., MacLean, Brendan X., Villén, Judit, MacCoss, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277451/
https://www.ncbi.nlm.nih.gov/pubmed/30510204
http://dx.doi.org/10.1038/s41467-018-07454-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277451/
https://www.ncbi.nlm.nih.gov/pubmed/30510204
http://dx.doi.org/10.1038/s41467-018-07454-w

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