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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals

Royal jelly is the queen-maker for the honey bee Apis mellifera, and has cross-species effects on longevity, fertility, and regeneration in mammals. Despite this knowledge, how royal jelly or its components exert their myriad effects has remained poorly understood. Using mouse embryonic stem cells a...

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Detalles Bibliográficos
Autores principales: Wan, Derrick C., Morgan, Stefanie L., Spencley, Andrew L., Mariano, Natasha, Chang, Erin Y., Shankar, Gautam, Luo, Yunhai, Li, Ted H., Huh, Dana, Huynh, Star K., Garcia, Jasmine M., Dovey, Cole M., Lumb, Jennifer, Liu, Ling, Brown, Katharine V., Bermudez, Abel, Luong, Richard, Zeng, Hong, Mascetti, Victoria L., Pitteri, Sharon J., Wang, Jordon, Tu, Hua, Quarta, Marco, Sebastiano, Vittorio, Nusse, Roel, Rando, Thomas A., Carette, Jan E., Bazan, J. Fernando, Wang, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277453/
https://www.ncbi.nlm.nih.gov/pubmed/30510260
http://dx.doi.org/10.1038/s41467-018-06256-4