Inhibition of MicroRNA-221 and 222 Enhances Hematopoietic Differentiation from Human Pluripotent Stem Cells via c-KIT Upregulation

The stem cell factor (SCF)/c-KIT axis plays an important role in the hematopoietic differentiation of human pluripotent stem cells (hPSCs), but its regulatory mechanisms involving microRNAs (miRs) are not fully elucidated. Here, we demonstrated that supplementation with SCF increases the hematopoiet...

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Detalles Bibliográficos
Autores principales: Lee, Ji Yoon, Kim, MyungJoo, Heo, Hye-Ryeon, Ha, Kwon-Soo, Han, Eun-Taek, Park, Won Sun, Yang, Se-Ran, Hong, Seok-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277561/
https://www.ncbi.nlm.nih.gov/pubmed/30396237
http://dx.doi.org/10.14348/molcells.2018.0244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277561/
https://www.ncbi.nlm.nih.gov/pubmed/30396237
http://dx.doi.org/10.14348/molcells.2018.0244

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