Cargando…

Inhibition of MicroRNA-221 and 222 Enhances Hematopoietic Differentiation from Human Pluripotent Stem Cells via c-KIT Upregulation

The stem cell factor (SCF)/c-KIT axis plays an important role in the hematopoietic differentiation of human pluripotent stem cells (hPSCs), but its regulatory mechanisms involving microRNAs (miRs) are not fully elucidated. Here, we demonstrated that supplementation with SCF increases the hematopoiet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Ji Yoon, Kim, MyungJoo, Heo, Hye-Ryeon, Ha, Kwon-Soo, Han, Eun-Taek, Park, Won Sun, Yang, Se-Ran, Hong, Seok-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277561/ https://www.ncbi.nlm.nih.gov/pubmed/30396237 http://dx.doi.org/10.14348/molcells.2018.0244

Ejemplares similares

Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
por: Kim, Hye-Ryun, et al.
Publicado: (2016)

Role of MicroRNAs-221/222 in Digestive Systems
por: Matsuzaki, Juntaro, et al.
Publicado: (2015)

Microrna-221 and Microrna-222 Modulate Differentiation and Maturation of Skeletal Muscle Cells
por: Cardinali, Beatrice, et al.
Publicado: (2009)

Overexpression of primary microRNA 221/222 in acute myeloid leukemia
por: Rommer, Anna, et al.
Publicado: (2013)

Reprogramming mechanisms influence the maturation of hematopoietic progenitors from human pluripotent stem cells
por: Heo, Hye-Ryeon, et al.
Publicado: (2018)

MicroRNA 221/222 cluster kicks out Timp-3 to inflame the liver
por: Menghini, Rossella, et al.
Publicado: (2018)

BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner
por: Jeong, Suji, et al.
Publicado: (2020)

Androgen receptor-mediated downregulation of microRNA-221 and -222 in castration-resistant prostate cancer
por: Gui, Bin, et al.
Publicado: (2017)

Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis
por: Xiao, Xi, et al.
Publicado: (2021)

MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
por: Chun-zhi, Zhang, et al.
Publicado: (2010)

Downregulation of miR-221/222 by a microRNA sponge promotes apoptosis in oral squamous cell carcinoma cells through upregulation of PTEN
por: Zhou, Lijie, et al.
Publicado: (2016)

Role of microRNAs 221/222 on Statin Induced Nitric Oxide Release in Human Endothelial Cells
por: Cerda, Alvaro, et al.
Publicado: (2015)

MicroRNA-221/222 Inhibits the Radiation-Induced Invasiveness and Promotes the Radiosensitivity of Malignant Meningioma Cells
por: Zhang, Qing, et al.
Publicado: (2020)

Regulation of microRNA‐221, ‐222, ‐21 and ‐27 in articular cartilage subjected to abnormal compressive forces
por: Stadnik, Paulina S., et al.
Publicado: (2020)

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours
por: Gits, C M M, et al.
Publicado: (2013)

Identification of transcriptional level variations in microRNA-221 and microRNA-222 as alternate players in the thyroid cancer tumor microenvironment
por: Khan, Rashida, et al.
Publicado: (2023)

Commentary: MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload-Induced Heart Failure
por: Schmitz, Boris, et al.
Publicado: (2018)

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling
por: Chistiakov, Dmitry A., et al.
Publicado: (2015)

Gastric Carcinogenesis in the miR-222/221 Transgenic Mouse Model
por: Choi, Boram, et al.
Publicado: (2017)

Role of miR-221/222 in Tumor Development and the Underlying Mechanism
por: Song, Qian, et al.
Publicado: (2019)

Influence of miR-221/222 on cardiomyocyte calcium handling and function
por: Knyrim, Maria, et al.
Publicado: (2021)

Muscarinic receptor activation in colon cancer selectively augments pro-proliferative microRNA-21, microRNA-221 and microRNA-222 expression
por: Larabee, Shannon M., et al.
Publicado: (2022)

MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer
por: Shah, Maitri Y, et al.
Publicado: (2011)

The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients
por: Zhang, Pengfei, et al.
Publicado: (2018)

miR-221/222 Target the DNA Methyltransferase MGMT in Glioma Cells
por: Quintavalle, Cristina, et al.
Publicado: (2013)

Genistein Promotes Skeletal Muscle Regeneration by Regulating miR-221/222
por: Shen, Linyuan, et al.
Publicado: (2022)

Generation of macrophage containing alveolar organoids derived from human pluripotent stem cells for pulmonary fibrosis modeling and drug efficacy testing
por: Heo, Hye-Ryeon, et al.
Publicado: (2021)

Regulation of CD4 Receptor and HIV-1 Entry by MicroRNAs-221 and -222 during Differentiation of THP-1 Cells
por: Lodge, Robert, et al.
Publicado: (2017)

Biodegradable and biocompatible cationic polymer delivering microRNA-221/222 promotes nerve regeneration after sciatic nerve crush
por: Song, Jialin, et al.
Publicado: (2017)

MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1
por: Lai, Tsai-Chun, et al.
Publicado: (2020)

MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination
por: Wigton, Eric J., et al.
Publicado: (2021)

Adipose and Plasma microRNAs miR-221 and 222 Associate with Obesity, Insulin Resistance, and New Onset Diabetes after Peritoneal Dialysis
por: Chan, Gordon Chun Kau, et al.
Publicado: (2022)

miR-21, miR-221, and miR-222 upregulation in lung cancer promotes metastasis by reducing oxidative stress and apoptosis
por: Tepebaşı, Muhammet Yusuf, et al.
Publicado: (2023)

Human pluripotent stem cell-derived alveolar epithelial cells are alternatives for in vitro pulmotoxicity assessment
por: Heo, Hye-Ryeon, et al.
Publicado: (2019)

miRNA-221 and miRNA-222 synergistically function to promote vascular calcification
por: Mackenzie, N C W, et al.
Publicado: (2014)

Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
por: Jiang, Xiuli, et al.
Publicado: (2018)

Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases
por: Song, Jialin, et al.
Publicado: (2017)

Circulating miR-221/222 expression as microRNA biomarker predicting tamoxifen treatment outcome: a case–control study
por: Patellongi, Ilhamjaya, et al.
Publicado: (2023)

MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker
por: Goto, Yusuke, et al.
Publicado: (2015)

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
por: Zhang, Chun-Zhi, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_j9olsvvg5rk8uin66gh39li01g