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FGF23 Induction of O-Linked N-Acetylglucosamine Regulates IL-6 Secretion in Human Bronchial Epithelial Cells

The hexosamine biosynthetic pathway (HBP) generates the substrate for the O-linked β-N-acetylglucosamine (O-GlcNAc) modification of proteins. The HBP also serves as a stress sensor and has been reported to be involved with nuclear factor of activated T-cells (NFAT) activation, which can contribute t...

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Detalles Bibliográficos
Autores principales: Krick, Stefanie, Helton, Eric Scott, Hutcheson, Samuel B., Blumhof, Scott, Garth, Jaleesa M., Denson, Rebecca S., Zaharias, Rennan S., Wickham, Hannah, Barnes, Jarrod W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277595/
https://www.ncbi.nlm.nih.gov/pubmed/30538676
http://dx.doi.org/10.3389/fendo.2018.00708