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The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections

Costimulatory and coinhibitory receptors play a key role in regulating immune responses to infection and cancer. Coinhibitory receptors include programmed cell death 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell immunoglobulin and ITIM domain (TIGIT), which suppress immu...

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Detalles Bibliográficos
Autores principales: Yasuma-Mitobe, Keiko, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277675/
https://www.ncbi.nlm.nih.gov/pubmed/30538707
http://dx.doi.org/10.3389/fimmu.2018.02755