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Promises and Pitfalls in the Use of PD-1/PD-L1 Inhibitors in Multiple Myeloma
In the biology of multiple myeloma (MM), immune dysregulation has emerged as a critical component for novel therapeutic strategies. This dysfunction is due to a reduced antigen presentation, a reduced effector cell ability and a loss of reactive T cells against myeloma, together with a bone marrow m...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277686/ https://www.ncbi.nlm.nih.gov/pubmed/30538704 http://dx.doi.org/10.3389/fimmu.2018.02749 |