Improved Biodistribution and Extended Serum Half-Life of a Bacteriophage Endolysin by Albumin Binding Domain Fusion

The increasing number of multidrug-resistant bacteria intensifies the need to develop new antimicrobial agents. Endolysins are bacteriophage-derived enzymes that degrade the bacterial cell wall and hold promise as a new class of highly specific and versatile antimicrobials. One major limitation to t...

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Detalles Bibliográficos
Autores principales: Seijsing, Johan, Sobieraj, Anna M., Keller, Nadia, Shen, Yang, Zinkernagel, Annelies S., Loessner, Martin J., Schmelcher, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277698/
https://www.ncbi.nlm.nih.gov/pubmed/30538696
http://dx.doi.org/10.3389/fmicb.2018.02927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277698/
https://www.ncbi.nlm.nih.gov/pubmed/30538696
http://dx.doi.org/10.3389/fmicb.2018.02927

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