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Revisiting the Concept of Targeting NFAT to Control T Cell Immunity and Autoimmune Diseases

The nuclear factor of activated T cells (NFAT) family of transcription factors, which includes NFAT1, NFAT2, and NFAT4, are well-known to play important roles in T cell activation. Most of NFAT proteins are controlled by calcium influx upon T cell receptor and costimulatory signaling results increas...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Ung, Kim, Li-Kyung, Choi, Je-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277705/
https://www.ncbi.nlm.nih.gov/pubmed/30538703
http://dx.doi.org/10.3389/fimmu.2018.02747