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Identification of a First Human Norovirus CD8(+) T Cell Epitope Restricted to HLA-A(*)0201 Allele

Norovirus (NoV) causes a substantial global burden of acute gastroenteritis in all age groups and the development of NoV vaccine is a high priority. There are still gaps in understanding of protective NoV-specific immunity. Antibody mediated immune responses have been widely studied, but in contrast...

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Detalles Bibliográficos
Autores principales: Malm, Maria, Vesikari, Timo, Blazevic, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277766/
https://www.ncbi.nlm.nih.gov/pubmed/30542352
http://dx.doi.org/10.3389/fimmu.2018.02782