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A Highly Active Form of XCL1/Lymphotactin Functions as an Effective Adjuvant to Recruit Cross-Presenting Dendritic Cells for Induction of Effector and Memory CD8(+) T Cells

The chemokine receptor XCR1 is known to be selectively expressed by cross-presenting dendritic cells (DCs), while its ligand XCL1/lymphotactin is mainly produced by activated CD8(+) T cells and natural killer cells. Recent studies have shown that XCL1-antigen fusion proteins efficiently induce CD8(+...

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Detalles Bibliográficos
Autores principales: Matsuo, Kazuhiko, Kitahata, Kosuke, Kawabata, Fumika, Kamei, Momo, Hara, Yuta, Takamura, Shiki, Oiso, Naoki, Kawada, Akira, Yoshie, Osamu, Nakayama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277777/
https://www.ncbi.nlm.nih.gov/pubmed/30542351
http://dx.doi.org/10.3389/fimmu.2018.02775