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A Highly Active Form of XCL1/Lymphotactin Functions as an Effective Adjuvant to Recruit Cross-Presenting Dendritic Cells for Induction of Effector and Memory CD8(+) T Cells
The chemokine receptor XCR1 is known to be selectively expressed by cross-presenting dendritic cells (DCs), while its ligand XCL1/lymphotactin is mainly produced by activated CD8(+) T cells and natural killer cells. Recent studies have shown that XCL1-antigen fusion proteins efficiently induce CD8(+...
Autores principales: | Matsuo, Kazuhiko, Kitahata, Kosuke, Kawabata, Fumika, Kamei, Momo, Hara, Yuta, Takamura, Shiki, Oiso, Naoki, Kawada, Akira, Yoshie, Osamu, Nakayama, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277777/ https://www.ncbi.nlm.nih.gov/pubmed/30542351 http://dx.doi.org/10.3389/fimmu.2018.02775 |
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