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Cyto-nuclear shuttling of afadin is required for rapid estradiol-mediated modifications of histone H3

Estrogens have been shown to rapidly regulate local signalling at synapses and within the nucleus. The result of these signalling events is to rapidly modulate synapse structure and function, as well as epigenetic mechanisms including histone modifications. Ultimately these mechanisms are thought to...

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Detalles Bibliográficos
Autores principales: Sellers, Katherine J., Watson, Iain A., Gresz, Rahel E., Raval, Pooja, Srivastava, Deepak P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277849/
https://www.ncbi.nlm.nih.gov/pubmed/30268521
http://dx.doi.org/10.1016/j.neuropharm.2018.09.041