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STIM Proteins and Orai Ca(2+) Channels Are Involved in the Intracellular Pathways Activated by TLQP-21 in RAW264.7 Macrophages

TLQP-21 is a neuropeptide which has been implicated in regulation of nociception and other relevant physiologic functions. Although recent studies identified C3a and gC1q receptors as targets for TLQP-21, its intracellular molecular mechanisms of action remain largely unidentified. Our aim was (i) t...

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Detalles Bibliográficos
Autores principales: Molteni, Laura, Rizzi, Laura, Bresciani, Elena, Meanti, Ramona, Fehrentz, Jean-Alain, Verdié, Pascal, Omeljaniuk, Robert J., Biagini, Giuseppe, Locatelli, Vittorio, Torsello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277904/
https://www.ncbi.nlm.nih.gov/pubmed/30542288
http://dx.doi.org/10.3389/fphar.2018.01386