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N-Phthalyl-l-Tryptophan (RG108), like Clozapine (CLO), Induces Chromatin Remodeling in Brains of Prenatally Stressed Mice

Schizophrenia (SZ), schizoaffective (SZA), and bipolar (BP) disorder are neurodevelopmental psychopathological conditions related, in part, to genetic load and, in part, to environmentally induced epigenetic dysregulation of chromatin structure and function in neocortical GABAergic, glutamatergic, a...

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Detalles Bibliográficos
Autores principales: Dong, Erbo, Locci, Valentina, Gatta, Eleonora, Grayson, Dennis R., Guidotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277925/
https://www.ncbi.nlm.nih.gov/pubmed/30397000
http://dx.doi.org/10.1124/mol.118.113415