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The possible molecular mechanisms of farnesol on the antifungal resistance of C. albicans biofilms: the regulation of CYR1 and PDE2

BACKGROUND: Farnesol has potential antifungal activity against Candida albicans biofilms, but the molecular mechanism of this activity is still unclear. Farnesol inhibits hyphal growth by regulating the cyclic AMP (cAMP) signalling pathway in C. albicans, and CYR1 and PDE2 regulate a pair of enzymes...

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Detalles Bibliográficos
Autores principales: Chen, Shengyan, Xia, Jinping, Li, Chengxi, Zuo, Lulu, Wei, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278051/
https://www.ncbi.nlm.nih.gov/pubmed/30509171
http://dx.doi.org/10.1186/s12866-018-1344-z