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Glycolysis inhibition via mTOR suppression is a key step in cardamonin-induced autophagy in SKOV3 cells

BACKGROUND: Autophagy occurs in cells that undergoing nutrient deprivation. Glycolysis rapidly supplies energy for the proliferation of cancer cells. Cardamonin inhibits proliferation and enhances autophagy by mTORC1 suppression in ovarian cancer cells. Here, we investigate the relationship between...

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Detalles Bibliográficos
Autores principales: Shi, Daohua, Zhao, Di, Niu, Peiguang, Zhu, Yanting, Zhou, Jintuo, Chen, Huajiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278091/
https://www.ncbi.nlm.nih.gov/pubmed/30514289
http://dx.doi.org/10.1186/s12906-018-2380-9