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The Contribution of the Descending Pain Modulatory Pathway in Opioid Tolerance

Opioids remain among the most effective pain-relieving therapeutics. However, their long-term use is limited due to the development of tolerance and potential for addiction. For many years, researchers have explored the underlying mechanisms that lead to this decreased effectiveness of opioids after...

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Detalles Bibliográficos
Autores principales: Lueptow, Lindsay M., Fakira, Amanda K., Bobeck, Erin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278175/
https://www.ncbi.nlm.nih.gov/pubmed/30542261
http://dx.doi.org/10.3389/fnins.2018.00886