Preparation of Enantiomeric β-(2′,5′-Dimethylphenyl)Bromolactones, Their Antiproliferative Activity and Effect on Biological Membranes

Three novel enantiomeric pairs of bromolactones possesing a 2,5-dimethylphenyl substituent at the β-position of the lactone ring have been synthesized from corresponding enantiomeric (E)-3-(2′,5′-dimethylphenyl)hex-4-enoic acids (4) by kinetically controlled bromolactonization with N-bromosuccinimid...

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Detalles Bibliográficos
Autores principales: Gładkowski, Witold, Włoch, Aleksandra, Pawlak, Aleksandra, Sysak, Angelika, Białońska, Agata, Mazur, Marcelina, Mituła, Paweł, Maciejewska, Gabriela, Obmińska-Mrukowicz, Bożena, Kleszczyńska, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278266/
https://www.ncbi.nlm.nih.gov/pubmed/30463384
http://dx.doi.org/10.3390/molecules23113035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278266/
https://www.ncbi.nlm.nih.gov/pubmed/30463384
http://dx.doi.org/10.3390/molecules23113035

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