Effects of Red Ginseng Extract on the Pharmacokinetics and Elimination of Methotrexate via Mrp2 Regulation

We aimed to investigate the effects of red ginseng extract (RGE) on the expression of efflux transporters and to study the pharmacokinetics of representative substrate. For this, rats received single or repeated administration of RGE (1.5 g/kg/day) for 1 and 2 weeks via oral gavage. mRNA and protein...

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Detalles Bibliográficos
Autores principales: Lee, Sowon, Kwon, Mihwa, Choi, Min-Koo, Song, Im-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278279/
https://www.ncbi.nlm.nih.gov/pubmed/30424502
http://dx.doi.org/10.3390/molecules23112948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278279/
https://www.ncbi.nlm.nih.gov/pubmed/30424502
http://dx.doi.org/10.3390/molecules23112948

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