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Rosmarinic Acid Derivatives’ Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer’s Disease

Inhibition of glycogen synthase kinase 3β (GSK-3β) is considered to be the central therapeutic approach against Alzheimer’s disease (AD). In the present study, boiled water extracts of the Kangen-karyu (KK) herbal mixture and its constituents were screened for GSK-3β inhibitory activity. KK is used...

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Detalles Bibliográficos
Autores principales: Paudel, Pradeep, Seong, Su Hui, Zhou, Yajuan, Park, Chan Hum, Yokozawa, Takako, Jung, Hyun Ah, Choi, Jae Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278281/
https://www.ncbi.nlm.nih.gov/pubmed/30413117
http://dx.doi.org/10.3390/molecules23112919