Synthesis of Jacaranone-Derived Nitrogenous Cyclohexadienones and Their Antiproliferative and Antiprotozoal Activities

The cytotoxic and antiprotozoal activities of the phytoquinoide, jacaranone, and related compounds have been an ongoing topic in recent drug discovery. Starting from the natural product-derived cyclohexadienone scaffold, a series of nitrogen-containing derivatives were synthesized and subsequently e...

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Detalles Bibliográficos
Autores principales: Presser, Armin, Lainer, Gunda, Kretschmer, Nadine, Schuehly, Wolfgang, Saf, Robert, Kaiser, Marcel, Kalt, Marc-Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278284/
https://www.ncbi.nlm.nih.gov/pubmed/30405045
http://dx.doi.org/10.3390/molecules23112902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278284/
https://www.ncbi.nlm.nih.gov/pubmed/30405045
http://dx.doi.org/10.3390/molecules23112902

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