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P27 Protects Cardiomyocytes from Sepsis via Activation of Autophagy and Inhibition of Apoptosis

BACKGROUND: It has been reported that p27Kip1 plays an important role not only in the inhibition of cyclin-dependent kinases but also in the regulation of autophagy under various metabolically related stress conditions, including glucose deprivation and endoplasmic reticulum stress. However, its eff...

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Detalles Bibliográficos
Autores principales: Zhao, Xianyuan, Qi, Hong, Zhou, Jiamin, Xu, Shuqi, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278300/
https://www.ncbi.nlm.nih.gov/pubmed/30478251
http://dx.doi.org/10.12659/MSM.912750