Anti-Leishmanial and Cytotoxic Activities of a Series of Maleimides: Synthesis, Biological Evaluation and Structure-Activity Relationship

In the present study, 45 maleimides have been synthesized and evaluated for anti-leishmanial activities against L. donovani in vitro and cytotoxicity toward THP1 cells. All compounds exhibited obvious anti-leishmanial activities. Among the tested compounds, there were 10 maleimides with superior ant...

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Detalles Bibliográficos
Autores principales: Fan, Yongxian, Lu, Yuele, Chen, Xiaolong, Tekwani, Babu, Li, Xing-Cong, Shen, Yinchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278306/
https://www.ncbi.nlm.nih.gov/pubmed/30400596
http://dx.doi.org/10.3390/molecules23112878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278306/
https://www.ncbi.nlm.nih.gov/pubmed/30400596
http://dx.doi.org/10.3390/molecules23112878

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