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Anti-Leishmanial and Cytotoxic Activities of a Series of Maleimides: Synthesis, Biological Evaluation and Structure-Activity Relationship

In the present study, 45 maleimides have been synthesized and evaluated for anti-leishmanial activities against L. donovani in vitro and cytotoxicity toward THP1 cells. All compounds exhibited obvious anti-leishmanial activities. Among the tested compounds, there were 10 maleimides with superior ant...

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Detalles Bibliográficos
Autores principales:	Fan, Yongxian, Lu, Yuele, Chen, Xiaolong, Tekwani, Babu, Li, Xing-Cong, Shen, Yinchu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278306/ https://www.ncbi.nlm.nih.gov/pubmed/30400596 http://dx.doi.org/10.3390/molecules23112878

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