TrypanocidalActivity of Natural Sesquiterpenoids Involves Mitochondrial Dysfunction, ROS Production and Autophagic Phenotype in Trypanosoma cruzi

Chagas disease is a neglected tropical disease that is caused by the protozoan Trypanosoma cruzi and represents a serious health problem, especially in Latin America. The clinical treatment of Chagas disease is based on two nitroderivatives that present severe side effects and important limitations....

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Detalles Bibliográficos
Autores principales: Bombaça, Ana Cristina Souza, Von Dossow, Daniela, Barbosa, Juliana Magalhães Chaves, Paz, Cristian, Burgos, Viviana, Menna-Barreto, Rubem Figueiredo Sadok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278339/
https://www.ncbi.nlm.nih.gov/pubmed/30373326
http://dx.doi.org/10.3390/molecules23112800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278339/
https://www.ncbi.nlm.nih.gov/pubmed/30373326
http://dx.doi.org/10.3390/molecules23112800

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