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TrypanocidalActivity of Natural Sesquiterpenoids Involves Mitochondrial Dysfunction, ROS Production and Autophagic Phenotype in Trypanosoma cruzi

Chagas disease is a neglected tropical disease that is caused by the protozoan Trypanosoma cruzi and represents a serious health problem, especially in Latin America. The clinical treatment of Chagas disease is based on two nitroderivatives that present severe side effects and important limitations....

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Detalles Bibliográficos
Autores principales:	Bombaça, Ana Cristina Souza, Von Dossow, Daniela, Barbosa, Juliana Magalhães Chaves, Paz, Cristian, Burgos, Viviana, Menna-Barreto, Rubem Figueiredo Sadok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278339/ https://www.ncbi.nlm.nih.gov/pubmed/30373326 http://dx.doi.org/10.3390/molecules23112800

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